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Stabroek News

Cloning associate admits pioneer faked cell results
published: Friday | December 16, 2005


South Korean scientist Hwang Woo-suk. - REUTERS

SEOUL, South Korea (AP):

A DOCTOR who collaborated with cloning pioneer Hwang Woo-suk said yesterday that the South Korean scientist had agreed to withdraw a key research paper after allegations that he faked data on the production of stem cells, news reports said.

Roh Sung-il, chairman of the board at Mizmedi Hospital, told KBS television Hwang had agreed to ask the journal Science to withdraw the paper, published in June to international acclaim. Roh provided human eggs for research by Hwang and was one of the co-authors of the article that detailed how individual stem cell colonies were created for 11 patients through cloning.

Roh also told MBC television that Hwang had pressured a former scientist at his lab to falsify data to make it look like there were 11 stem cell colonies.

In a separate report, a former researcher told MBC that Hwang ordered him to fabricate photos to make it appear there were 11 separate colonies.

"This is something I shouldn't have done," said the researcher, only identified by his last name Kim whose face wasn't shown. "I had no choice but to do it."

Nine of the embryonic stem cell lines Hwang had claimed were cloned in the paper were faked, Roh said, and the authenticity of the other two was unknown.

Roh told MBC that he heard from Hwang yesterday morning that there were also no embryonic stem cells remaining from the experiments because all colonies have since died in the lab.

"I heard some things that I wasn't aware of when I visited Professor Hwang at his request, that there are no embryonic stem cells," Roh told MBC, adding Hwang himself had been unaware there were no remaining stem cells.

Hwang didn't answer his phone and researchers from his lab at Seoul National University could not be immediately reached for comment.

Hwang was staying at the university's hospital, spokesman Yang Sung-ki said Thursday evening. The researcher has been undergoing treatment there for stress since last week, returning briefly to work for a day this week.

South Korean President Roh Moo-hyun, in the Philippines for a state visit, called for caution regarding the reports on Hwang's work. "Let's watch the situation," Roh said according to Choi In-ho, the president's vice spokesman.

Regarded as a world-leading researcher in stem cells, Hwang's work has recently come under a cloud of suspicion. Last month, he publicly apologised after admitting that, despite earlier denials, he used eggs donated by two junior female scientists in his lab _ a violation of international ethics guidelines.

Hwang also stepped down as head of the World Stem Cell Hub, an international project launched in October aimed at finding treatments for incurable diseases.

University of Pittsburgh researcher Gerald Schatten has already asked that Science remove him as the senior author of the report, citing questions about the paper's accuracy.

Hwang's team has admitted it made an error that led to duplicated photos accompanying the article, but editors of Science have so far stood by the paper's findings.

Amid the controversy, Seoul National University also announced this week it would conduct an internal probe into Hwang's research.

Scientists hope that stem cell research could one day lead to finding cures for hard-to-treat diseases such as paralysis and Parkinson's disease.

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